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Wencheng Liu Email Address


Job Title

Research Fellow

Voyager Therapeutics

One-Time Delivery. Benefits for a lifetime.


I have more than ten years of research experience in neurodegenerative diseases, including Alzheimer’s disease, Parkinson’s disease, and Huntington disease. My major contributions are in identifying anti-tau antibodies, generated using immunopurified PHF-tau as antigen, displaying significant efficacy against tau pathology. The highlight of my experience includes: 1.Led a program for antibody characterization, conducted in vivo efficacy studies with these antibodies using passive immunization, and established a spreading model for Alzheimer’s disease. 2.Led an efficacy study using vectored anti-tau antibody immunotherapy in animal models. As part of this project, I established several platforms for evaluating the efficacy of antibodies. These include an in vivo platform for efficacy studies with transgenic mice, as well as a platform to measure and evaluate the distribution and expression of antibodies delivered by vectors via different administration routes. 3.Investigated the role of how mitochondrial dysfunction in the progression of Parkinson Disease. 4.Generated Huntington transgenic mice for Huntington research by constructing a full length Huntington BAC that carried 226Q.

Last University
Graduated from Purdue University
Based in Greater Boston.

Other people working at Voyager Therapeutics:

Holger PatzkeVice President, Neuroscience and Head of Translational Biology
Jenna CarrollDirector Program Management
Steve Paul*****@voyagertherapeutics.com
Robert PietruskoChief Regulatory and Quality Officer
Yanqun ShuSenior Scientist II
Justin AubinSenior Research Associate
Martin GouletExpert Consultant
Andre TurennePresident and Chief Executive Officer
Kathleen HayesVice President, Human Resources
Allen NunnallyChief Business Officer
Kyle GrantDirector of Vector Production
M. Higgins********@voyagertherapeutics.com
Amy RenSenior Research Associate I
Todd CarterVice President, Head of Vector Engineering, Interim Head of Research
J. Hou****@voyagertherapeutics.com
Maria ScheelAssociate Director Vector Production
Bernard RavinaChief Medical Officer
S. Stetson********@voyagertherapeutics.com
Mark LohsenSenior Associate Scientist I
Jean KaufmanBiotech Human Resources Leader
Li LiuPrincipal Research Associate

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