Malkit Sami Email Address

Head of Process Development

Immunocore is a privately owned, clinical-stage, UK-based biotechnology company, focused on the discovery and development of novel T cell

CMC expert with 20 years industrial experience in the manufacture of Biologics. Extensive knowledge of microbial manufacture, characterisation, pre-formulation, scaling and process validation. Highly experienced in structure activity relationships of biologics (published several papers on crystal structures of clinically significant cytokines). Significant experience of selecting and managing contract research organisations for outsourced work. Well networked in biotech and pharmaceutical companies, with academics and contract research companies. Specialist knowledge of refolding of heterodimeric chains from inclusion bodies. Experience of DoE application for process validation and characterisation prerequisites for BLA filing Significant knowledge of protein modification with small drugs or PEGs.