Yonchu Jenkins Email Address

Senior Clinical Reseach Scientist

Calithera Biosciences, Inc. is a clinical-stage pharmaceutical company focused on discovering and developing novel small molecule drugs directed against tumor metabolism and tumor immunology targets for the treatment of cancer. Calithera’s lead product candidate, CB-839, is currently being evaluated in three Phase 1 clinical trials in solid and hematological cancers. CB-1158 is a first-in- class immuno-oncology metabolic checkpoint inhibitor targeting arginase, a critical immunosuppressive enzyme responsible for T-cell suppression by myeloid-derived suppressor cells. Arginase depletes arginine, a nutrient that is critical for the activation, growth and survival of the body’s cancer-fighting immune cells, known as cytotoxic T -cells. Calithera is headquartered in South San Francisco, California.

Extremely versatile senior research scientist with extensive experience in small molecule preclinical research and development. Project leadership experience from inception to IND-enabling stage. Also managed crossfunctional project teams and external collaborations with contract research organizations. Skilled, detail-oriented molecular and cellular biologist with research background in oncology, tumor metabolism, virology, and metabolic diseases. Effective communicator and public speaker, regularly represented project team at internal company-wide meetings and represented company at both corporate and national scientific meetings. Strong writing skills, with experience in writing regulatory and technical documents, as well as scientific publications.