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Susan Molineaux Email Address


Job Title

President and Chief Executive Officer

Calithera Biosciences

Calithera Biosciences, Inc. is a clinical-stage pharmaceutical company focused on discovering and developing novel small molecule drugs directed against tumor metabolism and tumor immunology targets for the treatment of cancer. Calithera’s lead product candidate, CB-839, is currently being evaluated in three Phase 1 clinical trials in solid and hematological cancers. CB-1158 is a first-in- class immuno-oncology metabolic checkpoint inhibitor targeting arginase, a critical immunosuppressive enzyme responsible for T-cell suppression by myeloid-derived suppressor cells. Arginase depletes arginine, a nutrient that is critical for the activation, growth and survival of the body’s cancer-fighting immune cells, known as cytotoxic T -cells. Calithera is headquartered in South San Francisco, California.


I have served as President, Chief Executive Officer and as a member of the board of directors at Calithera Biosciences since I co-founded the company in March 2010. Prior to Calithera, I co- founded Proteolix, Inc. in 2003 and served as Chief Scientific Officer and later as Chief Executive Officer in the company, prior to its acquisition by Onyx Pharmaceuticals, Inc. in 2009. I led the team that discovered the proteasome inhibitor carfilzomib (marketed as Kyprolis) and conducted the Phase 2 clinical trials that led to the accelerated approval of Kyprolis for the treatment of refractory multiple myeloma in 2012. Prior to founding Proteolix, I held various senior scientific and management positions at Rigel Pharmaceuticals, Inc., Praecis Pharmaceuticals Inc., and Merck & Co. I currently serve as a member of the board of directors of Geron Corporation, a biopharmaceutical company. I also serve as the Chairman of BayBio, Northern California’s Life Science Association. I received a B.S. degree in Biology from Smith College, a Ph.D. degree in Molecular Biology from Johns Hopkins University, and completed a postdoctoral fellowship at Columbia University.

Last University
Graduated from Smith College
Lives in South San Francisco.

Other people working at Calithera Biosciences:

Bong PhanExecutive Assistant
Peter ShwonekTechnician
Eric SjogrenSenior Vice President, Drug Discovery
Stephanie WongChief Financial Officer and Secretary
Susanne SteggerdaAssociate Director, Pharmacology and Toxicology
Sumita RayPrincipal
David B DemoSenior Vice President and Vice President, R and D Operations
Sunil AgarwalMember Board of Directors
Jennifer McNealeyChief Financial Officer
Keith OrfordChief Medical Officer
Curtis HechtChief Business Officer
Jennifer Yori PhDAssociate Director of Medical Affairs
Andy MackinnonAssociate Director of Biology
A. Rhodesa*****@calithera.com
Mike RyanCo-Founder and Chairman of the Board
Yonchu JenkinsSenior Clinical Reseach Scientist

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