Interventional Cardiologist and Advanced Heart Failure Specialist
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Dr. Kapur is a Professor of Medicine in the Division of Cardiology. He is a board-certified Interventional Cardiologist and Advanced Heart Failure/Cardiac Transplant specialist. His clinical expertise focuses on invasive hemodynamics, mechanical circulatory support, complex percutaneous coronary intervention, and interventional therapies for patients with advanced heart failure and cardiogenic shock. He established the first hybrid Interventional Heart Failure (IHF) fellowship at Tufts Medical Center. Dr. Kapur’s translational research focuses on advanced hemodynamics, acute and chronic heart failure, circulatory support device development, and cardioprotective mechanisms in the setting of acute myocardial infarction and heart failure. He was the first to develop and report the utility of the pulmonary artery pulsatility index (PAPi), which is a canonical measure of right heart failure. His laboratory was also the first to identify that unloading the left ventricle and delaying coronary reperfusion activates a cardioprotective signaling program that reduces myocardial damage during a heart attack. He is the principal investigator for multiple clinical trials focused on mechanical circulatory support, acute myocardial infarction, and cardiogenic shock. Dr. Kapur’s basic science laboratory focuses on molecular mechanisms governing maladaptive cardiac remodeling in heart failure. This laboratory has published several critical papers focused on the transforming growth factor beta (TGFb) family including novel functional roles for endoglin and BMP-9 in maladaptive cardiac remodeling. Dr. Kapur is the inventor on multiple patents and has co-founded several companies including preCARDIA, an award-winning device-based company acquired in 2021 that focuses on cardio-renal unloading for heart failure. He has extensive experience working with venture capital firms, early and late-stage start-up companies, and strategic industry partners. Dr. Kapur is the recipient of grant funding from the National Institutes of Health, American Heart Association, and several industry sponsors. He has served on multiple national and international committees involved with the American Heart Association, the American College of Cardiology, the Heart Failure Society of America, and the Society for Cardiovascular Angiography and Interventions.