Ariful Qadri Email Address

Senior Scientist

At MedImmune our core therapeutic areas are Oncology; Respiratory, Inflammation & Autoimmune, and Cardiovascular & Metabolic Disease.

Highly motivated in-vivo and in-vitro pharmacologist with extensive research experience in molecular biology, pharmacology and biochemistry for drug discovery projects. Skilled at designing and executing experiments in a wide variety of animal models for respiratory, cardiovascular, endocrine, immunology, Inflammation and neuro degenerative diseases. Proficient in conducting in ex vivo and in vitro cell based assays histology and Immuno histochemistry and Immuno Floresence techniques. Expert in conducting various biological and functional assays by using different platforms. Assisted in transgenic rodent animal model development. Expert in isolation of PBMCs from healthy and disease blood to do various cell assays by using blood cells. Expert in set up of ALI Culture technique to test compounds in healthy and diseased conditions by using primary epithelial cells from healthy and COPD patients. Expert in writing IACUC protocols for various animal studies. Well versed communication, leadership, team building and cross-functional working skills. Intrested in drug discovery for various human diseases. Specialties: Animal model development Dosing animals via IV,PO,SubQ,IM, IN, IT and IV. Basic and Classical Histology Assay development and assay Validation Immuno histochemistry, Immuno staining & immuno Floresence Isolation of PBMCs form Blood and separation of various cell types Cell culture techniques and ALI Culture set up FACS analysis ELISA, MSD, Luminex , Fluidigm assay Platforms Inhibition and cell Proliferation assays Apoptosis and Tunnel assays Islet isolation from Pancreas Molecular biology Techniques (PCR,qPCR, Fluidigm, RNA Seq) QuantiGene and Luminex techniques Gene expression techniques. Patient blood sample analysis. Study reports and Protocol submission.