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Catherine Penfold Email Address

abcdefghij@stjude.org

Job Title

Associate Scientist St Jude Children's Research Hospital

Company
SJCRH

St. Jude Children’s Research Hospital is leading the way the world understands, treats and defeats childhood cancer and other life-threatening diseases. St. Jude was established in 1962 and has helped to increase the childhood cancer survival rate from 20% to more than 80% since it first opened its doors. The institution is powered by the great generosity of its donors, which helps ensure that families never receive a bill from St. Jude for treatment, travel, housing or food--so they can focus on helping their child live.

Bio

Engineer and innovator with over 20 years of international experience, managing complex and cutting edge projects with research and clinical deliverables. Sector experience spans academic research, pharma, finance and healthcare, including healthcare IT production systems, big data analytics, diagnostic software creation, and machine learning. US Immigration Status: Permanent Resident (EB-1A Immigrant Greencard) ***Research Career Highlights*** Invented and demonstrated the patented use of bacterial artificial chromosomes for high precision, rapid, scalable manipulation of stem cells. Internationally recognized by EMBL curriculum as a critical milestone in genetic engineering, and precursor to CRISPR-Cas9 technology. Development and optimization of protocols for electron microscopy in situ RT-PCR validation of drug targets, implemented at global GSK locations. Development, validation, and optimization of machine learning pipelines which discovered metastatic drug targets from comparative gene expression analysis of both big and noisy datasets originating from cancer and stem cell lines. First to demonstrate long term cell survival following intercellular delivery of bioactive materials by nano-injection. First to demonstrate long term survival and protein expression from delivery of mRNA by nano-injection. Invented, validated, and distributed software used to identify genetic variants in children with rare disorders. Participation in a national competition to discover novel diagnostic approaches for big data. Optimized code and algorithms to return results in less than two hours from whole genome sequences, twenty minutes for exomes. Identified novel variants for known conditions, not served by routine genetic clinical testing, ending a combined diagnostic odyssey of over 40 years for 12 families. ***Healthcare Career Highlights*** Team contributions on implementation and monitoring of successful campus wide infection control measures, in alignment with national government directives, in a healthcare setting. Policy and SOP creation in collaboration with union representatives. Reporting to C-Suite executives, local and national government monitoring. Team contributions on creation, implementation and monitoring of successful de-identification and sample management IT solution campus wide. Collaboration management with Compliance, IT, Research & Development, and Clinical Departments to elicit and achieve consensus on requirements, in alignment with federal and state legislation, in a healthcare setting. Reporting to C-Suite executives.

Last University
Graduated from University of York
Location
Based in Memphis, Tennessee, United States.

Other people working at SJCRH:

Elizabeth ScottSupervisor Human Resources Talent Acquistion Specialists
Yuri Yanishevski PmpDirector of Information Technology Service Management
Anna RitzSenior Liaison Marketing Operations St Jude Children's Research Hospital
Keith PerrySenior Vice President and Chief Information Officer
John LeechSenior Director Global Revenue Talent Acquisition
Alicia PowersProcess Development Senior Scientist II
Alisha WilmothDirector, Media Partnerships St Jude Children's Research Hospital
Dana BottenfieldInstructional Designer
Molly FieldingEvent Chair for St Jude Birmingham Chapter
Alexandria GaryEvent Planner
Leigh WarrenPayroll Specialist
Darrell GentryManager Software Development and Research Informatics
Denise AndersonOwner and Sport and Fitness Trainer and Nutrition and Wellness Consultant
Brian ElrodChief Information Security Officer
Kumar Srivastava**********@stjude.org
Patrick O'keefeSenior Director Marketing Technology and Data Enablement
Andras SablauerSenior Strategic Advisor, Information Services
St JudeChildren's Research Hospital St Jude Children's Research Hospital
Jeremy HuntTeam Player
Megan TancrellSenior Regional Development Director
Linda HarrisDirector of Postdoctoral Talent Acquisition
Kiri NessAssistant Member
Kim NicholsFull Member, Department of Oncology; Director, Division of Cancer Predisposition
Le Ga******@stjude.org
John LambertDirector-Communications Innovation and Insights
Diane HeymanChief People Officer
Aimee HallSenior Vice President Digital
James McmurryManaging Director, Technology Services
Glenn HollowayChief Audit Officer
Brittany Neu**********@stjude.org
David JacquesSenior Vice President Products, Architecture, and Delivery St Jude Children's Research Hospital
George Bates**********@stjude.org

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