Director of Medicinal Chemistry
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Director and Scientific Leader responsible for recently driving two compounds into IND. Experienced and able to create success despite limited resources and manpower. I look at results not obstacles. Bringing to any new company accrued knowledge in multiple therapeutic areas such as protein-misfolding diseases (cystic fibrosis), oncology, CNS (analgesics), and CV/MET (antithrombotics and diabetes). Managing CRO medicinal chemistry teams and SAR development successfully delivering results. Excellent problem-solver and excelling at overcoming difficult challenges within strict time constraints. Ability to step into horizontal chemistry roles when needed. Supervising process development, scale up, and cGMP manufacture of APIs at external CMOs. My ability to present industry success is displayed by my >24 peer-reviewed publications and >9 patents/ patent applications. Adept at Knime workflow creation for data processing, assay requests, and database querying/ updating. Expertise: Medicinal chemistry, HTS hit triage, SAR development, lead optimization Organic synthesis Structure-based drug design CMC-drug substance process development, scale up, and cGMP manufacture CRO & CMO Management Intellectual Property Workflow Design & Implementation
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