Michael Hicks Email Address

Senior Integration Scientist

Human Longevity, Inc. (HLI) is the genomics-based, technology-driven company creating the world's largest and most comprehensive database of whole genome, phenotype and clinical data. HLI is developing and applying large scale computing and machine learning to make novel discoveries to revolutionize the practice of medicine. HLI's business also includes the HLI Health Nucleus, a genomic powered clinical research center which uses whole genome sequence analysis, advanced clinical imaging and innovative machine learning, along with curated personal health information, to deliver the most complete picture of individual health.

Computational and experimental biochemist with 10+ years experience in the analysis of protein function. Previous work in synthetic biology and metabolic engineering with interests in integrating systems level data (genomics, transcriptomics, metabolomics). Wet-lab: -Protein Biochemistry: bacteria and yeast expression, multiple purification techniques, SDS-PAGE and Western blot analysis, enzyme kinetics -Molecular Biology: DNA cloning, PCR, mutagenesis, P1 transduction, complementation, directed evolution -Biophysics: HPLC/MS, UV/Vis, Fluorescence, Circular dichroism, ITC Computational: -Bioinformatics: General tools including BLAST, multiple sequence and structure alignment programs, structure analysis using molecular visualization programs (Chimera, PyMol, VMD), phylogenetic analysis, protein similarity networks. -Python programming language, MySQL, shell scripting, working knowledge of R -Unix/Linux/Mac/Windows